Protein sorting signals: Simple peptides with complex functions

Gunnar Von Heijne

doi:10.1007/978-3-0348-9061-8_4

Protein sorting signals: Simple peptides with complex functions

Birkhäuser Basel eBooks: 67-76

Article 1995 English

Abstract

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Protein sorting signals provide good examples of peptides that can be studied both from a chemical and a biochemical perspective. Their simple designs and low degree of sequence conservation suggest that they are involved in rather non-specific peptide-lipid interactions, yet their ability to discriminate efficiently between the import machineries of different subcellular compartments rather points to the importance of peptide-receptor interactions. The study of protein sorting signals thus invites a cross-disciplinary approach.

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Protein sorting signals: Simple peptides with complex functions

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