Polygenic liability for anxiety in association with comorbid anxiety in multiple sclerosis

Kaarina Kowalec; Arvid Harder; Casandra Dolovich; Kathryn C. Fitzgerald; Amber Salter; Yi Lü; Çharles N. Bernstein; Shay‐Lee Bolton; Gary Cutter; John D. Fisk; Joel Gelernter; Lesley A. Graff; Sara Hägg; Carol Hitchon; Daniel Levey; Fred Lublin; Kyla A. McKay; Scott Burton Patten; Amit Patki; Murray B. Stein; Hemant K. Tiwari; Jerry S. Wolinsky; Ruth Ann Marrie

doi:10.1002/acn3.52025

Abstract

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Higher genetic burden for anxiety was associated with significantly increased odds of moderate anxious symptoms in MS of European genetic ancestry which did not differ from those with anxiety and no comorbid immune disease. This study suggests a genetic basis for anxiety in MS.

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Polygenic liability for anxiety in association with comorbid anxiety in multiple sclerosis

Abstract

Discussion(0)

Related publications

Polygenicity of Comorbid Depression in Multiple Sclerosis

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Depressive symptoms, anxiety and cognitive impairment: emerging evidence in multiple sclerosis

The association between anxiety and C-reactive protein (CRP) levels: Results from the Northern Finland 1966 Birth Cohort Study