Platinum-AIEgen coordination complex for imaging-guided annihilation of cisplatin-resistant cancer cells
Article 2020 en
Authors
ZH
Zhenyan He
YG
Yuting Gao
HZ
Haoke Zhang
Abstract
1 min read
We report the synthesis and comprehensive characterization of a new platinum-AIEgen coordination complex. Possessing a high 1O2 quantum yield of 0.75 in water, the complex efficiently kills cisplatin-resistant cancer cells under mild white light irradiation. Its strong fluorescence upon binding with proteins also enables direct visualization of its intracellular distribution.
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