Platelet-activating factor (PAF) was first shown to be released from rabbit basophils during an acute allergic IgE-mediated response with the capacity of activa- ting platelets, hence its name.'Full chemical char- acterization of the PAF molecule as an ether- linked phospholipid, 1-O-alkyl-2-acetyl-sn-glyceryl-3phosphorylcholine was later obtained.24There does not seem to be general agreement as to naming this molecule which is also referred to as Paf-acether, acetyl glyceryl ether phosphorylcholine (AGEPC), or anti-hypertensive polar renomedullary lipid (ARPL).However, the term platelet-activating factor or PAF
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