Antimicrobial Agents and Chemotherapy 49(12): 5127-5128
Article 2005 English
Authors
JT
Joel Tärning
NL
Niklas Lindegårdh
AA
Anna Annerberg
Abstract
1 min read
By using a sensitive new assay, the terminal elimination half-life of the antimalarial piperaquine in a healthy volunteer was estimated to be 33 days, which is longer than estimated previously. This result illustrates the importance of extended sampling duration and sensitive assay methodologies in characterizing the disposition of slowly eliminated antimalarial drugs.
Joel Tärning, Marcus J. Rijken, Rose McGready, Aung Pyae Phyo, Warunee Hanpithakpong, Nicholas Day, Sir Nicholas White, François Nosten, Niklas Lindegårdh
Joel Tärning, Elizabeth A. Ashley, Niklas Lindegårdh, Kasia Stepniewska, Lucy Phaiphun, Nicholas Day, Rose McGready, Michael Ashton, François Nosten, Sir Nicholas White
Kevin C. Kobylinski, Podjanee Jittamala, Borimas Hanboonkunupakarn, Sasithon Pukrittayakamee, Kanchana Pantuwatana, Siriporn Phasomkusolsil, Silas A. Davidson, Markus Winterberg, Richard M. Hoglund, Mavuto Mukaka, Rob W. van der Pluijm, Arjen M. Dondorp, Nicholas Day, Sir Nicholas White, Joel Tärning
Discussion(0)
No comments yet. Be the first to comment.