PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism

Changfeng Li; Ying Zhang; Xing Cheng; Hua Yuan; Shan Zhu; Jiao Liu; Qirong Wen; Yangchun Xie; Jinbao Liu; Guido Guido Kroemer; Daniel J. Klionsky; Michael T. Lotze; Herbert J. Zeh; Rui Kang; Daolin Tang

doi:10.1016/j.devcel.2025.07.018

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PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism

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PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism

Regnase-1 downregulation promotes pancreatic cancer through myeloid-derived suppressor cell-mediated evasion of anticancer immunity

TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis

[Mitochondrial control of apoptosis].

Mitochondrial control of apoptosis