Photochemical Activity of Black Phosphorus for Near‐Infrared Light Controlled In Situ Biomineralization

The photochemical activity of black phosphorus (BP) in near-infrared (NIR) light controlled in situ biomineralization is investigated. Owing to the excellent NIR absorption, irradiation with NIR light not only promotes degradation of BP into PO₄ ^3-, but also enhances the chemical activity to accelerate the reaction between PO₄ ^3- and Ca²⁺ and promote in situ biomineralization. Mineralization of hydrogels is demonstrated by the preparation of BP incorporated hydrogel (BP@Hydrogel) which delivers greatly improved biomineralization performance under NIR illumination. The biomineralization process which can be controlled by modulating the light irradiation time and location has a high potential in controlling the mechanical properties and osteoinductive ability in tissue engineering. This study also provides insights into the degradation, photochemical activity, and new biological/biomedical applications of BP.