Phenotypic assays and sequencing are less sensitive for the detection of resistance in mixed genotypes compared to point mutation assays

Kristel Van Laethem; Kristien Van Vaerenbergh; JC Schmit; S Sprecher; P Hermans; De Vroey; Rob Schuurman; Thomas Harrer; Myriam Witvrouw; Eric Van Wijngaerden; De Clercq Erik; Jan Desmyter; Anne‐Mieke Vandamme

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Phenotypic Assays and Sequencing Are Less Sensitive Than Point Mutation Assays for Detection of Resistance in Mixed HIV-1 Genotypic Populations

Kristel Van Laethem, Kristien Van Vaerenbergh, Jean‐Claude Schmit, S Sprecher, P. Hermans, Véronique De Vroey, Rob Schuurman, Thomas Harrer, Myriam Witvrouw, Eric Van Wijngaerden, Lieven Stuyver, Marc Van Ranst, Jan Desmyter, De Clercq Erik, Anne‐Mieke Vandamme

Article1999

Phenotypic Assays and Sequencing Are Less Sensitive Than Point Mutation Assays for Detection of Resistance in Mixed HIV-1 Genotypic Populations

Kristel Van Laethem, Kristien Van Vaerenbergh, Jean‐Claude Schmit, S Sprecher, P. Hermans, Véronique De Vroey, Rob Schuurman, Thomas Harrer, Myriam Witvrouw, Eric Van Wijngaerden, Lieven Stuyver, Marc Van Ranst, Jan Desmyter, De Clercq Erik, Anne‐Mieke Vandamme

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Immunohistochemistry Is Highly Sensitive and Specific for the Detection of V600E BRAF Mutation in Melanoma

Georgina V. Long, James S. Wilmott, David Capper, Matthias Preusser, Yuxiao E. Zhang, John F. Thompson, Richard Kefford, Andreas von Deimling, Richard A Scolyer

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Phenotypic multi-nucleoside resistance linked to the Q151M mutation is enhanced under the selective pressure of acyclic nucleotide analogs but reduced by foscarnet

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Sex ratio of the mutation frequencies in haemophilia A: coagulation assays and RFLP analysis.

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Phenotypic assays and sequencing are less sensitive for the detection of resistance in mixed genotypes compared to point mutation assays

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Phenotypic Assays and Sequencing Are Less Sensitive Than Point Mutation Assays for Detection of Resistance in Mixed HIV-1 Genotypic Populations

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