Phenolic and polysaccharidic extracts of Suillus collinitus: chemical characterization, growth inhibitory activity and induction of cell cycle arrest in a breast cancer cell line

The Northeast of Portugal is one of the European regions with higher mushrooms biodiversity. Mushrooms are a powerful source of new compounds, including low-molecular-weight (LMW, e.g. phenolic compounds) and high-molecular-weight (HMW, e.g polysaccharides) compounds, with potential antitumor and immunostimulating properties [1,2]. Furthermore, they may have potential as functional foods and sources of novel molecules. The aim of this work was to study the antitumor potential of the wild edible ectomycorrhizal mushroom, Suillus collinitus, collected from Northeast Portugal, and to characterize their LMW and HMW compounds.