Pharmacokinetics of Oral Doxycycline during Combination Treatment of Severe Falciparum Malaria
Antimicrobial Agents and Chemotherapy 49(4): 1622-1625
Article 2005 English
Authors
PN
Paul N. Newton
JC
Jean-François Chaulet
AB
Alan Brockman
Abstract
1 min read
The pharmacokinetics of oral doxycycline administered at 200 mg every 24 h were investigated in 17 patients recovering from severe Plasmodium falciparum malaria. The data suggest that the doses of doxycycline currently recommended (circa 3.5 mg/kg of body weight daily) may not be optimal.
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