Pharmacokinetic Study of Rectal Artesunate in Children with Severe Malaria in Africa

Caterina Fanello; Richard M. Hoglund; Sue J. Lee; Daddy K. Kayembe; Pauline Ndjowo; Charlie Kabedi; Benjamin B. Badjanga; Phettree Niamyim; Joel Tärning; Charles J. Woodrow; Melba Gomes; Nick Day; Sir Nicholas White; Marie Onyamboko

doi:10.1128/aac.02223-20

Abstract

1 min read

When severe malaria is suspected in children, the WHO recommends pretreatment with a single rectal dose of artesunate before referral to an appropriate facility. This was an individually randomized, open-label, 2-arm, crossover clinical trial in 82 Congolese children with severe

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