Over the last 4 decades, percutaneous coronary intervention has evolved dramatically and is now an acceptable treatment option for patients with advanced coronary artery disease. However, trialists have struggled to establish the respective roles for percutaneous coronary intervention and coronary artery bypass graft surgery, especially in patients with multivessel disease and unprotected left-main stem coronary artery disease. Several pivotal trials and meta-analyses comparing these 2 revascularization strategies have enabled the relative merits of each technique to be established with regard to the type of ischemic syndrome, the coronary anatomy, and the patient’s overall comorbidity. Precision medicine with individualized prognosis is emerging as an important method of selecting treatment. However, the never-ending advancement of technology, in conjunction with the emergence of novel pharmacological agents, will in the future continue to force us to reconsider the evolving question: “Which treatment strategy is better and for which patient?”
Stuart J. Head, Milan Milojevic, Joost Daemen, Jung‐Min Ahn, Eric Boersma, Evald Høj Christiansen, Michaël Domanski, Michael E. Farkouh, Marcus Flather, Valentı́n Fuster, Mark A. Hlatky, Niels Ramsing Holm, Whady Hueb, Masoor Kamalesh, Young‐Hak Kim, Timo H. Mäkikallio, Friedrich W. Mohr, Grigorios Papageorgiou, Seung‐Jung Park, Alfredo E. Rodríguez, Joseph F. Sabik, Rod Stables, Gregg W. Stone, Patrick W. Serruys, A. Pieter Kappetein
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