Pentraxin 3 deficiency protects from the metabolic inflammation associated to diet-induced obesity
Article 2019 en
Authors
FB
Fabrizia Bonacina
AM
Annalisa Moregola
RP
Rémi Porte
Abstract
1 min read
Our results support a critical role for PTX3 in the onset of obesity by promoting inflammation and limiting adipose tissue vascularization and delineate PTX3 targeting as a valuable strategy for the treatment of adipose tissue-associated inflammatory response.
Relber Aguiar Gonçales, Hélder Novais Bastos, Cláudio Duarte‐Oliveira, Daniela Antunes, Oksana Sokhatska, Maria Jacob, Rui Rolo, Cláudia F. Campos, Sérgio Daishi Sasaki, Alessia Donato, Sarah N. Mapelli, Sandra Costa, Conceição Souto Moura, Luís Delgado, António Morais, Egídio Torrado, Frank L. van de Veerdonk, Thomas Weichhart, John D. Lambris, Ricardo Silvestre, Cecília Garlanda, Alberto Mantovani, Cristina Cunha,
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