Level of PTX3 is independently associated with atherosclerosis and manifest cardiovascular disease but not early vessel pathology. Unlike C-reactive protein, PTX3 is not a component of the classic acute phase response (systemic inflammation) but appears to be more specific for vascular inflammation.
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Enrico Brunetta, Marco Folci, Barbara Bottazzi, Maria De Santis, Alessandro Protti, Sarah N. Mapelli, Roberto Leone, Ilaria My, Monica Bacci, Veronica Zanon, Gianmarco Spata, Andrea Gianatti, Marina Sironi, Claudio Angelini, Cecília Garlanda, Michele Ciccarelli, Maurizio Cecconi, Alberto Mantovani
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