Partial Inhibition Of The Key Glycolytic Enzyme Pfkfb3 In Myeloid Cells Impacts Whole-Body Immune Cell And Liver Metabolism, But Not Atherogenesis.

Joost D. de Bruijn; Kim van Kuijk; Mitchell Bijnen; Marion J. Gijbels; Kristiaan Wouters; Peter Carmeliet; Judith C. Sluimer

doi:10.1016/j.atherosclerosis.2019.06.055

Related publications

Article2023

Partial myeloid inhibition of key glycolytic enzyme PFKFB3 increases hepatic steatosis and inflammation, but does not affect atherosclerosis

R. Tillie, Joost D. de Bruijn, Ross Dobie, Javier Perales-Patón, Kim van Kuijk, Marion J. Gijbels, Lieve Temmerman, Yanal Ghosheh, Gijs H. Goossens, Peter Carmeliet, Klaus Ley, Neil C. Henderson, Julio Sáez-Rodríguez, Kristiaan Wouters, Judith C. Sluimer

Article2021

Partial Inhibition of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase-3 (PFKFB3) Enzyme in Myeloid Cells Does Not Affect Atherosclerosis

R. Tillie, Jenny de Bruijn, Javier Perales-Patón, Lieve Temmerman, Yanal Ghosheh, Kim van Kuijk, Marion J. Gijbels, Peter Carmeliet, Klaus Ley, Julio Sáez-Rodríguez, Judith C. Sluimer

Letter2016

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

Anna Rita Cantelmo, Lena-Christin Conradi, Aleksandra Brajic, Jermaine Goveia, Joanna Kalucka, Andreas Pircher, Pallavi Chaturvedi, Johanna Hol Fosse, Bernard Thienpont, Laure-Anne Teuwen, Sandra Schoors, Bram Boeckx, Joris Vriens, Anna Kuchnio, Koen Veys, Bert Cruys, Lise Finotto, Lucas Treps, Tor Espen Stav-Noraas, Francesco Bifari, Peter C. Stapor, Ilaria Decimo, Kim R. Kampen,

Article2010

Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression

Michael Maes

Article2014

Metabolism of stromal and immune cells in health and disease

Bart Ghesquière, Brian W. Wong, Anna Kuchnio, Peter Carmeliet