P6240Long term cardiovascular risk prediction in Real-World atrial fibrillation patients: Validation of the 2MACE score in the FANTASIIA registry

The A Body Shape index (ABSI) is calculated based on waist circumference, height and BMI and is a validated measure of visceral adiposity. In the general population, the ABSI has been shown to be an independent risk factor for premature mortality. Purpose: The purpose of this study was to investigate the power of ABSI to predict cardiovascular events in patients with peripheral artery disease (PAD). Methods: We prospectively recorded cardiovascular events in 319 patients with sonographically verified PAD over a mean follow-up time of 7.22.1 years. Results: At baseline, the ABSI was significantly higher in patients with type 2 diabetes (T2DM) than in those who did not have diabetes (19.51.9 vs. 14.01.1; p<0.001). Prospectively, the ABSI significantly predicted the incidence of cardiovascular events (n=57) both univariately ]; p<0.001) and after adjustment for age, gender, smoking, LDL cholesterol, HDL cholesterol, hypertension and T2DM (standardized adjusted HR 1.17 [1.08-1.29]; p=0.010); also T2DM significantly predicted cardiovascular events in this fully adjusted model ]; p<0.001).