P1900Development of a risk score for incident atrial fibrillation on 471,446 chinese subjects. The C2HEST score

Atrial fibrillation -epidemiology / Atrial fibrillation ablation 407 vs. 0.39 per 1000 person-year). Non-adjusted hazard ratio (HR) (95% confidence interval [CI]) of salt intake for the new AF was 1. 169 (1.108-1.234). In analysis where subjects were divided into gender-specific quartiles according to the baseline salt intake (salt intake; 7.41.7, 9.51.8, 11.32.0 and 14.33.0 g/day in the first, second, third, and fourth quartiles, respectively), the incidence of AF were increased across the quartiles (0.73, 1.31, 1.72, and 1.99 per 1000 personyears). However, multivariate Cox proportional hazard analysis adjusted for age, gender, body mass index, systolic blood pressure, heart rate, serum creatinine, uric acid, fasting plasma glucose, low-density lipoprotein cholesterol, triglyceride, haemoglobin, B-type natriuretic peptide and current smoking habit at baseline revealed that salt intake did not predict the new AF (HR:0.970, 95% CI: 0.906-1.039). Conclusions: Although salt intake is associated with the development of AF as well as the presence of AF in the general population, other factors rather than salt intake have much more prominent impact on the development of AF. This suggests the complementary role of salt intake for the prediction of AF.