Organization of the dermal matrix impacts the biomechanical properties of skin

A.K. Langton; Helen K. Graham; J. C. McConnell; Michael J. Sherratt; Christopher Em Griffiths; Rachel Watson

doi:10.1111/bjd.15353

Abstract

1 min read

Maintenance of skin architecture - both epidermal morphology and elastic fibre arrangement - is essential for optimal skin biomechanical properties. Disruption to underlying skin architecture, as observed in the young white Northern European forearm, compromises biomechanical function.

Related publications

Article2019

Ageing significantly impacts the biomechanical function and structural composition of skin

A.K. Langton, Helen K. Graham, Christopher Em Griffiths, Rachel Watson

Letter2022

Influence of menopause and hormone replacement therapy on epidermal ageing and skin biomechanical function

Kieran T. Mellody, Alexandra C. Kendall, Jonathan R. Wray, April Foster, A.K. Langton, Patrick Costello, Victoria Newton, Mike Bell, Christopher Em Griffiths, Anna Nicolaou, Rachel Watson, Suzanne M. Pilkington

Article2020

Remodelling of fibrillin-rich microfibrils by solar-simulated radiation: impact of skin ethnicity

A.K. Langton, Mark Hann, Patrick Costello, Poonam Halai, Christopher Em Griffiths, Michael J. Sherratt, Rachel Watson

Article2015

P16INK4a Positive Cells in Human Skin Are Indicative of Local Elastic Fiber Morphology, Facial Wrinkling, and Perceived Age

Mariëtte E. C. Waaijer, David A. Gunn, Peter D. Adams, Jeff S. Pawlikowski, Christopher Em Griffiths, Diana van Heemst, P. Eline Slagboom, Rudi G. J. Westendorp, Andrea B. Maier

Article2020

The systemic influence of chronic smoking on skin structure and mechanical function

A.K. Langton, Evridiki Tsoureli‐Nikita, Holly Merrick, Xuegen Zhao, Christina Antoniou, Alexander Stratigos, Riaz Akhtar, Brian Derby, Michael J. Sherratt, Rachel Watson, Christopher Em Griffiths