Organic–Inorganic Nanospheres with Responsive Molecular Gates for Drug Storage and Release

Catch and release: Bridged silsesquioxanes act as organic–inorganic precursors for nanospheres to encapsulate bioactive molecules for drug-delivery applications. The nanosystems (see picture) are constructed from an liposomal core containing bioactive molecules and an network shell formed by silica and organic ester fragments that can act as responsive molecular gates. Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.