Oral Contraceptives and the Risk of Myocardial Infarction

Bea C. Tanis; Maurice A. A. J. van den Bosch; Jeanet M. Kemmeren; V. Manger Cats; Frans M. Helmerhorst; Ale Algra; Yolanda van der Graaf; Frits R. Rosendaal

doi:10.1056/nejmoa003216

Abstract

1 min read

An association between the use of oral contraceptives and the risk of myocardial infarction has been found in some, but not all, studies. We investigated this association, according to the type of progestagen included in third-generation (i.e., desogestrel or gestodene) and second-generation (i.e., levonorgestrel) oral contraceptives, the dose of estrogen, and the presence or absence of prothrombotic mutations.

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