Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene

Jennifer R. Anthony; Larry C. Anthony; Farnaz Nowroozi; Gina Kwon; Jack D. Newman; Jay D Keasling

doi:10.1016/j.ymben.2008.07.007

Back

Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene

Article 2008 en

Discussion(0)

No comments yet. Be the first to comment.

Related publications

Article2009

High-Level Production of Amorpha-4,11-Diene, a Precursor of the Antimalarial Agent Artemisinin, in Escherichia coli

Hiroko Tsuruta, Christopher J. Paddon, Diana G. Eng, Jacob R. Lenihan, Tizita Horning, Larry C. Anthony, Rika Regentin, Jay D Keasling, Neil S. Renninger, Jack D. Newman

Article2013

Application of targeted proteomics and biological parts assembly in E. coli to optimize the biosynthesis of an anti-malarial drug precursor, amorpha-4,11-diene

Han Min Woo, Gregory Murray, Tanveer S. Batth, Nilu Prasad, Paul D. Adams, Jay D Keasling, Christopher J. Petzold, Taek Soon Lee

Article2006

Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli

Douglas J. Pitera, Christopher J. Paddon, Jack D. Newman, Jay D Keasling

Article2007

Increased β-Carotene Production in Recombinant Escherichia coli Harboring an Engineered Isoprenoid Precursor Pathway with Mevalonate Addition

Myung Suk Choi, Jae‐Yean Kim, Deok‐Kun Oh, Jay D Keasling, Seon-Won Kim, Sang‐Hwal Yoon, Hye-Min Park, Jueun Kim, Sook-Hee Lee

Article2006

High‐level production of amorpha‐4,11‐diene in a two‐phase partitioning bioreactor of metabolically engineered <i>Escherichia coli</i>

Jack D. Newman, Jessica Marshall, Michelle C. Y. Chang, Farnaz Nowroozi, Eric M. Paradise, Douglas J. Pitera, Karyn L. Newman, Jay D Keasling