Nucleoside analogues : chemistry, biology, and medical applications

Nucleotide Conformations: Rules and Exceptions.- Nuclear Magnetic Resonance Studies of Nucleoside Conformational Properties.- Methods of Nucleoside Synthesis.- Chemical Transformations of the Sugar Moiety of Nucleosides.- Chemistry of Naturally Occurring Pyrimidine Nucleosides and Analogues.- Chemistry of the Heterocyclic Moiety of Purine Nucleosides and Some Closely Related Analogues.- The Mechanisms of Inhibition of Cellular and Viral Multiplication by Aranucleosides and Aranucleotides.- Uptake and Metabolism of Purine Nucleosides and Purine Nucleoside Analogues by Cells.- Basis for the Selective Antiviral and Antitumour Activity of Pyrimidine Nucleoside Analogues.- Development of Antiherpes Virus Agents on the Basis of Virus Induced Enzymes.- Test Systems for Evaluating the Antiviral Activity of Nucleoside Analogues.- Test Systems for Evaluating the Antitumour Activity of Nucleoside Analogues.- Success of Antiviral Therapy Involves Cooperative Immune Responses.- The Clinical Uses of Nucleoside Analogues in Malignant Disease.- Industrial Development of New Drugs.- Participants.