Nonsteroidal Anti-inflammatory Drugs and Cyclooxygenase-2 Inhibitors for Primary Prevention of Colorectal Cancer: A Systematic Review Prepared for the U.S. Preventive Services Task Force — Alaa Rostom (2007) | RDL Network
Nonsteroidal Anti-inflammatory Drugs and Cyclooxygenase-2 Inhibitors for Primary Prevention of Colorectal Cancer: A Systematic Review Prepared for the U.S. Preventive Services Task Force
Article 2007 en
Authors
AR
Alaa Rostom
CD
Catherine Dubé
GL
Gabriela Lewin
Abstract
1 min read
Cyclooxygenase-2 inhibitors and NSAIDs reduce the incidence of colonic adenomas. Nonsteroidal anti-inflammatory drugs also reduce the incidence of CRC. However, these agents are associated with important cardiovascular events and gastrointestinal harms. The balance of benefits to risk does not favor chemoprevention in average-risk individuals.
Manon Cairat, A. Fournier, Neil Murphy, Carine Biessy, Augustin Scalbert, Sabina Rinaldi, Anne Tjønneland, Anja Olsen, Kim Overvad, Patrick Arveux, Marie‐Christine Boutron‐Ruault, Claire Cadeau, Renée T. Fortner, Rudolf Kaaks, Heiner Boeing, Krasimira Aleksandrova, Petra H. Peeters, Carla H. van Gils, Nicholas J. Wareham, Kay‐Tee Khaw, Dagfinn Aune, Elio Riboli, Marc J. Gunter,
.webp){kind=small}
Discussion(0)
No comments yet. Be the first to comment.