NK cells beat T cells at early breast cancer control
Editorial Material 2020 en
Authors
AB
Aitziber Buqué
NB
Norma Bloy
GP
Giulia Petroni
Abstract
1 min read
Cancer immunosurveillance generally relies on adaptive immune programs executed by CD8+ T cells. Our findings demonstrate that CD8+ T cells fail to control early oncogenesis in a mouse model of luminal B breast cancer and suggest that natural killer (NK) cells may instead play a predominant role in this setting.
Aitziber Buqué, Norma Bloy, María Pérez-Lanzón, Kristina Iribarren, Juliette Humeau, Jonathan Pol, Sarah Lévesque, Laura Mondragón, Takahiro Yamazaki, Ai Sato, Fernando Aranda, Sylvère Durand, Alexandre Boissonnas, Jitka Fučíková, Laura Senovilla, David Enot, Michal Hensler, Margerie Kremer, Gautier Stoll, Yang Hu, Chiara Massa, Silvia C. Formenti, Barbara Seliger, Olivier Elemento, Radek Špíšek, Fabrice André, Laurence Zitvogel, Suzette Delaloge, Guido Guido Kroemer, Lorenzo Galluzzi
Chenyu Zhang, Charles Chien, Eglė Jurgaitytė, K. Sakiyama, Alissa Bockman, Yeara Jo, Seung Won Lee, Stephanie Silveria, Elizabeth Andrews, Abigail Mende, Lily Zhang, K. Christopher García, Allon Wagner, Michel DuPage, David H Raulet
Discussion(0)
No comments yet. Be the first to comment.