NIR-II Bioimaging

Fluorescent probes that emit in the second near-infrared region (NIR-II, 1000–1700 nm) possess unique advantages, including low photodamage and deep penetration into biological samples. Notably, NIR-II optical imaging can achieve tissue penetration as deep as 5–20 mm, which is critical for biomedical sensing and clinical applications. Many researchers have developed NIR-II dyes to meet the needs of modern biomedicine. This chapter will review the NIR-II fluorescent probes for biomolecules and for therapeutic applications.