MRI in Leber's hereditary optic neuropathy: the relationship to multiple sclerosis
Article 2014 en
Authors
LM
Lucy Matthews
CE
Christian Enzinger
FF
Franz Fazekas
Abstract
1 min read
A blinded review of conventional brain MRIs shows that patients with LMS have a scan appearance indistinguishable from MS. Mitochondrial dysfunction could be a common pathophysiological pathway in the formation of white matter lesions. There appears to be a strong female influence on the radiological appearance as well as clinical development of MS in patients with LHON.
Roberta Messina, Maria A. Rocca, Stefania Bianchi Marzoli, Melissa Petrolini, Iacopo Milesi, Fatima Darvizeh, Francesco Bandello, Gıancarlo Comı, Andrea Falini, Massimo Filippi
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