Moloney Sarcoma Virus-Induced Tumors in Mice: Inhibition or Stimulation by (Poly rI){middle dot}(Poly rC)

SummaryThese studies demonstrate a major effect of age of animals on the effect of (poly rI)·(poly rC) on Moloney sarcoma virus-induced tumors. In 4-6-day-old mice, tumors appeared later in the treated than in the control group, whereas in 20-day-old mice, treatment enhanced tumor formation.