Molecular Processing of Tau Protein in Progressive Supranuclear Palsy: Neuronal and Glial Degeneration — Alejandra Martínez-Maldonado (2021) | RDL Network
Molecular Processing of Tau Protein in Progressive Supranuclear Palsy: Neuronal and Glial Degeneration
Article 2021 en
Authors
AM
Alejandra Martínez-Maldonado
MO
Miguel Ángel Ontiveros‐Torres
CH
Charles R. Harrington
Abstract
1 min read
Phosphorylated tau was as abundant in PSP as in AD. The development of eNFTs from both glial cells and neuronal bodies suggests that truncated tau species, different from those observed in AD, could be present in PSP. Additional studies on truncated tau within PSP lesions could improve our understanding of the pathological processing of tau and help identify a discriminatory biomarker for AD and PSP.
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