Mitochondrial Fusion Suppresses Tau Pathology-Induced Neurodegeneration and Cognitive Decline

Luwen Wang; Mengyu Liu; Ju Gao; Amber M. Smith; Hisashi Fujioka; Jingjing Liang; George Perry; Xinglong Wang

doi:10.3233/jad-215175

Abstract

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These in vivo findings suggest that promoted mitochondrial fusion suppresses toxic tau accumulation and associated neurodegeneration, which may protect against the progression of AD and related tauopathies.

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