Microwave-Assisted Synthesis of Biotin Conjugates with Quinolone Antibiotics via Amino Acids
Article 2014 en
Authors
AK
Alan R. Katritzky
SP
Siva S. Panda
RN
Roman N. Naumov
Abstract
1 min read
Benzotriazole-activated biotin was utilized as a versatile building block for the efficient and convenient synthesis of novel biotin conjugates with quinolone antibiotics via amino acid linkers under microwave irradiation. The products are obtained in yields of 70–91% with retention of chirality.
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