MicroRNA-184 is a downstream effector of albuminuria driving renal fibrosis in rats with diabetic nephropathy
Article 2017 en
Authors
CZ
Cristina Zanchi
DM
Daniela Macconi
PT
Piera Trionfini
Abstract
1 min read
These results suggest that miR-184 may act as a downstream effector of albuminuria through LPP3 to promote tubulointerstitial fibrosis, and offer the rationale to investigate whether targeting miR-184 in association with albuminuria-lowering drugs may be a new strategy to achieve fully anti-fibrotic effects in diabetic nephropathy.
Wouter B.A. Eijkelkamp, Zhongxin Zhang, Giuseppe Remuzzi, Hans‐Henrik Parving, Mark E. Cooper, William F. Keane, Shahnaz Shahinfar, Gilbert W. Gleim, Barry M. Brenner, Dick de Zeeuw
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