Methodological approaches for personalised medicine: protocol for a series of scoping reviews
Article 2020 en
Authors
RB
Rita Banzi
CG
Chiara Gerardi
MF
Maddalena Fratelli
Abstract
1 min read
This is the protocol for a series of scoping reviews that will map the general concept of methods for personalised medicine, to set the basis for the discussion on robustness and reproducibility of personalised medicine development programmes. The final goal is the identification of standards and needs in terms of methodology of data generation, management, analysis and interpretation to improve clinical studies in personalised medicine. For the purpose of this review, four main aspects of the general concept of personalised medicine will be analysed: Methods for stratification and validation cohorts Methods for machine learning applied to stratification Pre-clinical methods for translational development of treatment options and treatments selection Methods for clinical trials in personalised medicine
Vibeke Fosse, Emanuela Oldoni, Florence Biétrix, Alfredo Budillon, Evangelos P. Daskalopoulos, Maddalena Fratelli, Björn Gerlach, Peter Groenen, Sabine M. Hölter, Julia M. L. Menon, Ali Mobasheri, Nikki Osborne, Merel Ritskes‐Hoitinga, Bettina Ryll, Elmar Schmitt, Anton Ussi, Antoni L. Andreu, Emmet McCormack, Rita Banzi, Jacques Demotes‐Mainard, Paula Garcia, Chiara Gerardi, Enrico Glaab, Josep María Haro, Frank Hulstaert, Lorena San Miguel, Judit Subirana Mirete, Albert Sánchez‐Niubò, Raphaël Porcher, Armin Rauschenberger, M. Rodriguez, Cecilia Superchi, Teresa Margarita Torres López
Vibeke Fosse, Emanuela Oldoni, Chiara Gerardi, Rita Banzi, Maddalena Fratelli, Florence Biétrix, Anton Ussi, Antoni L. Andreu, Emmet McCormack, The PERMIT Group
Vibeke Fosse, Emanuela Oldoni, Chiara Gerardi, Rita Banzi, Maddalena Fratelli, Florence Biétrix, Anton Ussi, Antoni L. Andreu, Emmet McCormack, The PERMIT Group
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