The present invention relates to compositions and methods for cancer diagnosis, treatment and drug screening. In particular, the present invention provides compositions and methods for targeting the nuclear translocation of IkB kinase-.alpha. (IKK.alpha.) and the IKK.alpha.-mediated suppression of Maspin expression observed in metastatic prostate cancer cells.
Pedram Kharaziha, Patricia Q. Rodriguez, Qiao Li, Helene Rundqvist, A-C Björklund, Martin Augsten, Anders Ullén, Lars Egevad, Peter Wiklund, Sten Nilsson, Guido Guido Kroemer, Dan Grandér, Theocharis Panaretakis
Richard J. Rebello, Eric Kusnadi, Donald P. Cameron, Helen Pearson, Analia Lesmana, Jennifer R. Devlin, Denis Drygin, Ashlee K. Clark, Laura H. Porter, John Pedersen, Shahneen Sandhu, Gail P. Risbridger, Richard B. Pearson, Ross D. Hannan, Luc Furic
Discussion(0)
No comments yet. Be the first to comment.