Metabolomics profiles associated with SARS-CoV-2 -IgG serostatus as an alternative diagnostic approach

Mariam M Al Eissa; Muath ben shaded; Monera S. M. S. Alrukhayes; Ahdab Alsaieedi; Yousef Mall; Afshan Masood; Sami S. Almudrra; Khaled Alabdulkareem; Khalid H. AlAnazi; Assim A. Alfadda; Ahmed A. Albarraq; Abdullah Mohamed Asiri; Hani Jokhdar; Anas Abdel Rahman; Reem Almalki; Randh AlAhmari; Raghad AlQurashi; Esraa A. Hawsa

doi:10.1016/j.jiph.2026.103155

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Metabolomics profiles associated with SARS-CoV-2 -IgG serostatus as an alternative diagnostic approach

Article 2026 en

Abstract

1 min read

Our findings identify metabolomic alterations associated with SARS-CoV-2 infection between IgG-positive and IgG-negative individuals. The identified metabolites are involved in regulating lipid metabolism, immune response, and the inflammatory signaling pathways. The results offer preliminary hypothesis generating insights into the underlying changes that may inform future research on host-immune interactions in COVID-19. Changes in these metabolites need to be validated in larger and independent cohorts.

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