Measurement of allantoin and uric acid in human body fluids. A potential index of free-radical reactions <i>in vivo</i>? — Martin Grootveld (1987) | RDL Network
Free-radical attack upon uric acid generates allantoin [Ames, Cathcart, Schwiers & Hochstein (1981) Proc. Natl. Acad. Sci. U.S.A. 78, 6858-6862]. Methods are described for the accurate measurement of uric acid and allantoin in human body fluids. The concentrations of uric acid and allantoin in human serum and synovial fluid are reported. It is suggested that measurement of changes in allantoin concentration may be a useful index of free-radical reactions taking place in vivo.
Jan Gruber, Soon Yew Tang, Andrew M. Jenner, Ian Mudway, Anders Blomberg, Annelie Behndig, Katherine Kasiman, Jetty Chung‐Yung Lee, Raymond C.S. Seet, Wenxia Zhang, Christopher Chen, Frank J. Kelly, Barry Halliwell
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