Mammary carcinoma: toward a realistic mouse model of incurable cancers

María Pérez-Lanzón; Maria Chiara Maiuri; Carlos López-Otı́n; Guido Guido Kroemer

doi:10.1080/2162402x.2023.2240613

Abstract

1 min read

As long as breast cancer (BC) stays under immunosurveillance, it can be controlled by treatments eliciting anticancer immune responses. However, once BC escapes immunosurveillance, it becomes therapeutically uncontrollable. A paper in the Journal for ImmunoTherapy of Cancer describes a new hormone receptor-positive BC cell line generating incurable tumors in C57BL/6 mice.

Related publications

Article2023

New hormone receptor-positive breast cancer mouse cell line mimicking the immune microenvironment of anti-PD-1 resistant mammary carcinoma

María Pérez-Lanzón, Vincent Carbonnier, Pierre Cordier, Fatima Domenica Elisa De Palma, Adriana Petrazzuolo, Christophe Klein, Floriane Arbaretaz, Khady Mangane, Gautier Stoll, Isabelle Martins, Helene Fohrer Ting, Juliette Paillet, Sophie Mouillet‐Richard, Delphine Le Corre, Wenjjin Xiao, Marine Sroussi, Chantal Desdouets, Pierre Laurent‐Puig, Jonathan Pol, Carlos López-Otı́n, Maria Chiara Maiuri, Guido Guido Kroemer

Article2024

Preclinical models of breast cancer: B6BC, a transplantable hormone receptor-positive C57BL/6 mouse cell line

Maria Chiara Maiuri, Carlos López-Otı́n, Guido Guido Kroemer, María Pérez-Lanzón

Article2020

Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer

Aitziber Buqué, Norma Bloy, María Pérez-Lanzón, Kristina Iribarren, Juliette Humeau, Jonathan Pol, Sarah Lévesque, Laura Mondragón, Takahiro Yamazaki, Ai Sato, Fernando Aranda, Sylvère Durand, Alexandre Boissonnas, Jitka Fučíková, Laura Senovilla, David Enot, Michal Hensler, Margerie Kremer, Gautier Stoll, Yang Hu, Chiara Massa, Silvia C. Formenti, Barbara Seliger, Olivier Elemento, Radek Špíšek,

Article2022

Systematic Investigation of the Diagnostic and Prognostic Impact of LINC01087 in Human Cancers

Fatima Domenica Elisa De Palma, Vincent Carbonnier, Francesco Salvatore, Guido Guido Kroemer, Jonathan Pol, Maria Chiara Maiuri

Article2013

Immunological effects of chemotherapy in spontaneous breast cancers

Guido Guido Kroemer, Lorenzo Galluzzi, Laurence Zitvogel