In this issue of Cancer Cell, Haybaeck et al. unravel the role of lymphotoxin pathway in the development of hepatocellular carcinoma (HCC). Aberrant activation of this cascade in mice livers recapitulates the stages of fibrosis and inflammation that precedes human liver cancer, providing a novel family of potential therapeutic targets.
María Luz Martínez‐Chantar, Mercedes Vázquez–Chantada, Usue Ariz, Núria Martínez, Marta Varela‐Rey, Zigmund Luka, Antonieta Capdevila, Juan Lantero‐Rodriguez, Ana M. Aransay, Rune Matthiesen, Heping Yang, Diego F. Calvisi, Manel Esteller, Mario F. Fraga, Shelly C. Lu, Conrad Wagner, José M. Mato
Anita K. Mehta, Kira Bettermann, Eva Lederer, Christina Ernst, Sonja M. Kessler, Kensuke Kojima, Xintong Chen, Yujin Hoshida, Bryan C. Fuchs, Vendula Švendová, Michael G. Schimek, Monika Mach, Michael R. Speicher, Tatjana Stojaković, Thomas M. Magin, Pavel Strnad, Michael Trauner, Alexandra K. Kiemer, Snorri S. Thorgeirsson, Michael Karin, Josep M. Llovet, Kurt Zatloukal, ,
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