Longitudinal Assessment of Multiple Sclerosis with the Brain‐Age Paradigm
Article 2020 en
Authors
JC
James H. Cole
JR
Joel Raffel
TF
Tim Friede
Abstract
1 min read
The brain-age paradigm is sensitive to MS-related atrophy and clinical progression. A higher brain-PAD at baseline was associated with more rapid disability progression and the rate of change in brain-PAD related to worsening disability. Potentially, "brain-age" could be used as a prognostic biomarker in early-stage MS, to track disease progression or stratify patients for clinical trial enrollment. ANN NEUROL 2020 ANN NEUROL 2020;88:93-105.
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