Longer illness duration is associated with greater individual variability in functional brain activity in Schizophrenia, but not bipolar disorder

Julia Gallucci; Edith Pomarol‐Clotet; Aristotle N. Voineskos; Amalia Guerrero‐Pedraza; Sílvia Alonso-Lana; Eduard Vieta; Raymond Salvador; Colin Hawco

doi:10.1016/j.nicl.2022.103269

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Eduard Vieta

Longer illness duration is associated with greater individual variability in functional brain activity in Schizophrenia, but not bipolar disorder

Article 2022 en

Authors

JG
Julia Gallucci
EP
Edith Pomarol‐Clotet
AV
Aristotle N. Voineskos

Abstract

1 min read

An increase in variability was observed in the schizophrenia group related to illness duration, beyond the effects of normal aging, implying illness-related deterioration of cognitive networks. This has clinical implications for considering long-term trajectories in schizophrenia and progressive neural and cognitive decline which may be amiable to novel treatments.

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Longer illness duration is associated with greater individual variability in functional brain activity in Schizophrenia, but not bipolar disorder

Abstract

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