Limited Diagnostic Capacities of Two Commercial Assays for the Detection of <i>Leptospira</i> Immunoglobulin M Antibodies in Laos — Stuart D. Blacksell (2006) | RDL Network
Limited Diagnostic Capacities of Two Commercial Assays for the Detection of <i>Leptospira</i> Immunoglobulin M Antibodies in Laos
Clinical and Vaccine Immunology 13(10): 1166-1169
Article 2006 English
Authors
SB
Stuart D. Blacksell
LS
Lee D. Smythe
RP
Rattanaphone Phetsouvanh
Abstract
1 min read
The diagnostic utility of immunochromatographic (Leptotek) and enzyme-linked immunosorbent assay (ELISA; Panbio) tests for the detection of Leptospira immunoglobulin M antibodies was assessed in febrile adults admitted in Vientiane, Laos. Both tests demonstrated poor diagnostic accuracy using admission serum (Leptotek sensitivity of 47.3% and specificity of 75.5%: ELISA sensitivity of 60.9% and specificity of 65.6%) compared to the Leptospira “gold standard” microscopic agglutination test.
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