Skip to content
RDL
Network
Ekosistem
Uygulama değiştir
EN
Hakkımızda
SSS
Giriş yap
Başla
Lactate cannot substitute for alanine in D4T-based anti-HIV nucleotide prodrugs-despite efficient esterase-mediated hydrolysis — Christopher McGuigan (1998) | RDL Network
Back
Cite
Save
Save for later
Share
Home
Publications
Lactate cannot substitute for alanine in D4T-based anti-HIV nucleotide prodrugs-despite efficient esterase-mediated hydrolysis
Shared by
De Clercq Erik
KU Leuven
Lactate cannot substitute for alanine in D4T-based anti-HIV nucleotide prodrugs-despite efficient esterase-mediated hydrolysis
Article
1998
en
Authors
+3 more
CM
Christopher McGuigan
DC
Dominique Cahard
CB
Carlo Ballatore
Discussion
(0)
Sign in
to like and join the discussion.
No comments yet. Be the first to comment.
Related publications
Article
1999
ChemInform Abstract: Lactate Cannot Substitute for Alanine in D4T‐Based Anti‐HIV Nucleotide Prodrugs — Despite Efficient Esterase‐Mediated Hydrolysis.
Christopher McGuigan
,
Dominique Cahard
,
Carlo Ballatore
,
Adam Siddiqui
,
De Clercq Erik
,
Jan Balzarini
Article
1998
Synthesis and Anti-HIV Activity of some Novel Chain-Extended Phosphoramidate Derivatives of d4T (Stavudine): Esterase Hydrolysis as a Rapid Predictive Test for Antiviral Potency
Christopher McGuigan
,
H-W Tsang
,
PW Sutton
,
De Clercq Erik
,
Jan Balzarini
Article
1999
Design and Synthesis of Lipophilic Phosphoramidate d4T-MP Prodrugs Expressing High Potency Against HIV in Cell Culture: Structural Determinants for in Vitro Activity and QSAR
Adam Siddiqui
,
Christopher McGuigan
,
Carlo Ballatore
,
Fabio Zuccotto
,
Ian H. Gilbert
,
De Clercq Erik
,
Jan Balzarini
Article
1999
Simple mono-derivatisation of the aryl moiety of D4A and DDA-based phosphoramidate prodrugs significantly enhances their anti-HIV potency in cell culture
Adam Siddiqui
,
Christopher McGuigan
,
Carlo Ballatore
,
Orson Wedgwood
,
De Clercq Erik
,
Jan Balzarini
Article
2000
Phosphoramidate Derivatives of Stavudine as Inhibitors of HIV: Unnatural Amino Acids May Substitute for Alanine
Christopher McGuigan
,
L. Bidois
,
Aziz Hiouni
,
Carlo Ballatore
,
De Clercq Erik
,
Jan Balzarini
Discussion(0)
No comments yet. Be the first to comment.