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Lactate cannot substitute for alanine in D4T-based anti-HIV nucleotide prodrugs-despite efficient esterase-mediated hydrolysis — Christopher McGuigan (1998) | RDL Network
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Lactate cannot substitute for alanine in D4T-based anti-HIV nucleotide prodrugs-despite efficient esterase-mediated hydrolysis
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De Clercq Erik
KU Leuven
Lactate cannot substitute for alanine in D4T-based anti-HIV nucleotide prodrugs-despite efficient esterase-mediated hydrolysis
Article
1998
en
Authors
+3 more
CM
Christopher McGuigan
DC
Dominique Cahard
CB
Carlo Ballatore
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Related publications
Article
1999
ChemInform Abstract: Lactate Cannot Substitute for Alanine in D4T‐Based Anti‐HIV Nucleotide Prodrugs — Despite Efficient Esterase‐Mediated Hydrolysis.
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Simple mono-derivatisation of the aryl moiety of D4A and DDA-based phosphoramidate prodrugs significantly enhances their anti-HIV potency in cell culture
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