Kinase MEKK1 is required for CD40-dependent activation of the kinases Jnk and p38, germinal center formation, B cell proliferation and antibody production

Ewen Gallagher; Thomas Enzler; Atsushi Matsuzawa; Amy Anzelon-Mills; Dennis C. Otero; Ryan G. Holzer; Edith M. Janssen; Min Gao; Michael Karin

doi:10.1038/ni1421

Related publications

Dataset

Faculty Opinions recommendation of Mcl-1 is essential for germinal center formation and B cell memory.

Stefano Casola

Article2021

B cell–intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice

Michelle Sue Jann Lee, Takeshi Inoue, Wataru Ise, Julia Matsuo-Dapaah, James B. Wing, Burcu Temizoz, Kouji Kobiyama, Tomoya Hayashi, Ashwini Patil, Shimon Sakaguchi, Anna Katharina Simon, Jelena S. Bezbradica, Satoru Nagatoishi, Kouhei Tsumoto, Jun‐ichiro Inoue, Akira Shizuo, Tomohiro Kurosaki, Ken J. Ishii, Cevayir Coban

The Journal of Experimental Medicine

Article1997

A p38 MAP kinase inhibitor SB203580 inhibits CD28-dependent T cell proliferation and IL-2 production

Stephen G. Ward, Richard V. Parry, Jane S. Matthews, Luke O'neill

Biochemical Society Transactions

Article2003

IKKβ Is Required for Peripheral B Cell Survival and Proliferation

Zhiwei Li, Sidne A. Omori, Tord Labuda, Michael Karin, Robert C. Rickert

Article2009

MyD88 is required for viral-induced B cell activation and intestinal IgA production (44.20)

Sarah E. Blutt, Akira Shizuo, Lynn B. Dustin, Margaret E. Conner

The Journal of Immunology