Objective: to describe the initial experience in Colombia of locally advanced melanoma treated by isolated limb perfusion and compare the response rate of our melanoma subtypes with the literature.Methods: a descriptive, retrospective study of a series of patients selected between 2007 and 2016.Qualitative variables were analyzed with proportions and frequencies, and quantitative variable with central tendency measures and measures of dispersion.Results: 11 patients were treated by isolated limb perfusion.After the treatment, seven patients (63.6%) had partial response, two patients (18.2%) had stable disease and two patients (18.2%) had disease progression.Five patients (45.5%) had mild complications.Conclusions: Isolated limb perfusion is still an important treatment strategy for locally advanced melanoma, with the goal of improving the patient quality of life.The response can change according to the type of melanoma, and could be smaller in patients with acral lentiginous and nodular melanoma, although we cannot make this conclusion with this type of study because it has low power and lack of a comparison group.
Kong-Bing Tan, Marc Moncrieff, John F. Thompson, Stanley W. McCarthy, Helen M. Shaw, Michael J. Quinn, Ling-Xi Lawrence Li, Kerry A. Crotty, Jonathan R. Stretch, Richard A Scolyer
Reinhard Dummer, Shahneen Sandhu, Wilson H. Miller, Marcus O. Butler, Matthew H. Taylor, Lucie Heinzerling, Christian U. Blank, Eva Muñoz‐Couselo, Howard A. Burris, Michael A. Postow, Bartosz Chmielowski, Mark R. Middleton, Carola Berking, Jessica C. Hassel, Anja Gesierich, Cornelia Mauch, Joseph F. Kleha, Anna Polli, Allison S. Harney, Alessandra di Pietro, Paolo A. Ascierto
Zeynep Eroglu, Dae Won Kim, Douglas B. Johnson, Alain P. Algazi, Rodrigo Ramella Munhoz, Elizabeth Liniker, Ben L. Kong, Neharika Khurana, Bartosz Chmielowski, Jeffrey A. Sosman, Richard A Scolyer, Matteo S. Carlino, Michael A. Postow, Wen‐Jen Hwu, Georgina V. Long, Antoni Ribas
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