Is there a link between the use of adalimumab and Henoch–Schönlein purpura?

Dear Sir, We read with great interest the recent contribution by Marques et al.1 They reported a case of Henoch–Schonlein purpura (HSP) following treatment with adalimumab for ileo-colic Crohn's disease and speculated the deposition of anti-tumor necrosis factor (TNF)/TNF immune complexes in small capillaries, direct drug toxicity on vessel walls, the autoantibody …