Intramolecular C–C coupling of 2,6-disubstituted-1-bromoaryls for dihydrophenanthridines

Vijay Singh; Puspendra Singh; Harkesh B. Singh; Ray J. Butcher

doi:10.1016/j.tetlet.2012.06.087

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Intramolecular C–C coupling of 2,6-disubstituted-1-bromoaryls for dihydrophenanthridines

Tetrahedron Letters 53(34): 4591-4594

Article 2012 English

Abstract

1 min read

The reaction of 2,6-disubstituted-1-bromoaryl imines with sodium borohydride under reflux condition leads to an intramolecular cyclization through C–Br and C–H coupling without any transition-metal catalyst, furnishing 5,6-dihydrophenanthridine and phenanthridine derivatives.

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