Interferon and Its Inducers—A Never-Ending Story: “Old” and “New” Data in a New Perspective

The discovery of interferon (IFN), as an antiviral substance, by Isaacs and Lindenmann in 1957 De Somer's original attempts were aimed at determining the mode of action of IFN [2], whereas Merigan's work focused on trying to understand the role of IFN in human viral diseases