Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma

Yangchun Xie; Shan Zhu; Meizuo Zhong; Manhua Yang; Xiaofan Sun; Jinbao Liu; Guido Guido Kroemer; Michael T. Lotze; Herbert J. Zeh; Rui Kang; Daolin Tang

doi:10.1053/j.gastro.2017.07.036

Related publications

Article2009

The Aurora B kinase inhibitor AZD1152 sensitizes cancer cells to fractionated irradiation and induces mitotic catastrophe

Yungan Tao, Céline Leteur, Julien Caldéraro, Fiona Girdler, Zhang Ping, V. Frascogna, Mariana Varna, Paule Opolon, Maria Castedo, Jean Bourhis, Guido Guido Kroemer, Éric Deutsch

Article2017

Computationally-guided optimization of small-molecule inhibitors of the Aurora A kinase–TPX2 protein–protein interaction

D. J. A. Cole, M. Janecek, Jamie E. Stokes, Maxim Rossmann, John C. Faver, Grahame J. McKenzie, Ashok R. Venkitaraman, Marko Hyvönen, David R. Spring, David J. Huggins, William L. Jorgensen

Chemical Communications

Article2021

Genetic inhibition of RIPK3 ameliorates functional outcome in controlled cortical impact independent of necroptosis

Limin Wu, Joon Yong Chung, Tian Cao, Gina Jin, William J Edmiston, Suzanne E. Hickman, Emily Levy, Jordyn A. Whalen, Eliza Sophie LaRovere Abrams, Alexei Degterev, Eng H. Lo, Lorenzo Tozzi, David Kaplan, Joseph El Khoury, Michael J. Whalen

Article2017

A Case of Pancreatic Carcinoma in situ Diagnosed by Repeated Pancreatic Juice Cytology

Takeshi Miyata, Mamoru Takenaka, Shunsuke Omoto, Ken Kamata, Kosuke Minaga, Kentaro Yamao, Hajime Imai, Masatoshi Kudo

Article2007

Enhancement of radiation response in p53-deficient cancer cells by the Aurora-B kinase inhibitor AZD1152

Yungan Tao, Zhang Ping, Fiona Girdler, V. Frascogna, Maria Castedo, Jean Bourhis, Guido Guido Kroemer, Éric Deutsch