Increased Osteoid Formation in BMP-2–Loaded Silk-Based Screws
Article 2016 en
Authors
PK
Pieter G. L. Koolen
DH
Dylan S. Haas
KK
Kuylhee Kim
Abstract
1 min read
The BMP-2-loaded silk-based fixation device in this study exhibited characteristics comparable to the current nonloaded silk screws with regard to integration and biocompatibility. However, functionalization of silk screws with BMP-2 appeared to allow for more organized collagen and osteoid deposition after 3 and 6 months and may increase the potential of successful remodeling.
Vassilis Karageorgiou, Michael Tomkins, Robert Fajardo, Lorenz Meinel, Brian S. Snyder, Katherine Wade, Jake Y. Chen, Gordana Vunjak‐Novakovic, David Kaplan
P. C. Bessa, Elizabeth R. Balmayor, Mariana T. Cerqueira, Tommaso Rada, Manuela E. Gomes, Nuno M. Neves, Helena S. Azevedo, Margarida Casal, Rui L Reis
Discussion(0)
No comments yet. Be the first to comment.