INCREASED NON-PROTEIN-BOUND IRON AND DECREASED PROTECTION AGAINST SUPEROXIDE-RADICAL DAMAGE IN CEREBROSPINAL FLUID FROM PATIENTS WITH NEURONAL CEROID LIPOFUSCINOSES

JohnM.C. Gutteridge; Barry Halliwell; D. A. Rowley; Tuomas Westermarck

doi:10.1016/s0140-6736(82)90492-5

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Barry Halliwell

National University of Singapore

INCREASED NON-PROTEIN-BOUND IRON AND DECREASED PROTECTION AGAINST SUPEROXIDE-RADICAL DAMAGE IN CEREBROSPINAL FLUID FROM PATIENTS WITH NEURONAL CEROID LIPOFUSCINOSES

The Lancet 320(8296): 459-460

Article 1982 English

Authors

JG
JohnM.C. Gutteridge
Barry Halliwell
National University of Singapore
DR
D. A. Rowley

Abstract

1 min read

Cerebrospinal fluid from patients with neuronal ceroid lipofuscinoses (infantile or Santavuori-Haltia type and juvenile type or Batten's disease) has a higher concentration of non-protein-bound iron and lower antioxidant activity than that of controls. These changes may contribute to the pathology of the disorders.

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INCREASED NON-PROTEIN-BOUND IRON AND DECREASED PROTECTION AGAINST SUPEROXIDE-RADICAL DAMAGE IN CEREBROSPINAL FLUID FROM PATIENTS WITH NEURONAL CEROID LIPOFUSCINOSES

Abstract

Discussion(0)

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